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  4. Recombinant Mouse Myeloid cell surface antigen CD33 (Cd33), partial

Recombinant Mouse Myeloid cell surface antigen CD33 (Cd33), partial

  • 中文名称：
    Recombinant Mouse Myeloid cell surface antigen CD33(Cd33),partial,Yeast
  • 货号：
    CSB-YP730931MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Myeloid cell surface antigen CD33(Cd33),partial,Yeast
  • 货号：
    CSB-EP730931MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Myeloid cell surface antigen CD33(Cd33),partial,Yeast
  • 货号：
    CSB-EP730931MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Myeloid cell surface antigen CD33(Cd33),partial,Yeast
  • 货号：
    CSB-BP730931MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Myeloid cell surface antigen CD33(Cd33),partial,Yeast
  • 货号：
    CSB-MP730931MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cd33
  • Uniprot No.：
    Q63994
  • 别名：
    Cd33; Siglec3Myeloid cell surface antigen CD33; Sialic acid-binding Ig-like lectin 3; Siglec-3; CD antigen CD33
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Preferentially binds sialic acid to the short O-linked glycans of certain mucins.
  • 基因功能参考文献：
    1. Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs. PMID: 25320078
    2. CD33-related Siglec-E recognizes the intact neuron and has neuroprotective function by preventing phagocytosis. PMID: 24227736
    3. mCD33 is expressed on myeloid precursors in the bone marrow PMID: 12773563
    4. SOCS3 inhibited the CD33-induced block on cytokine-induced proliferation. SOCS3 and its target protein CD33 are degraded concomitantly concomitantly. PMID: 17008544
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family
  • 组织特异性：
    Expressed on myeloid precursors in the bone marrow. In the peripheral blood, mostly expressed on granulocytes.
  • 数据库链接：

    KEGG: mmu:12489

    STRING: 10090.ENSMUSP00000004728

    UniGene: Mm.140157

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