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IL2RA

IL2RA,全名为Interleukin-2 Receptor Alpha,又称CD25(Cluster of Differentiation 25),是一种细胞表面受体,属于白细胞介素-2(Interleukin-2,IL-2)受体家族。是IL-2受体的α亚单位,在免疫细胞表面广泛表达,特别是在T淋巴细胞(T细胞)中高表达。IL2RA的高表达与T细胞活化状态密切相关,是T细胞应答的一个重要标志。IL2RA在调节免疫应答和T细胞功能平衡方面发挥重要作用。在某些免疫疾病和自身免疫性疾病中,IL2RA的异常表达可能导致免疫平衡的紊乱,从而引发疾病,因此被认为是免疫治疗的一个重要靶点。通过调控IL2RA的功能,可以调节T细胞的活化和功能,从而在免疫治疗中发挥重要的作用。

更多相关阅读:IL2RA(CD25):CD4+CD25+Tregs亚群最特异性标志物,抑制效应T细胞,免疫领域热点分子!

热销产品

IL2RA Recombinant Monoclonal Antibody CSB-RA011649MA1HU

验证数据

ELISA
CSB-RA011649MA1HU ELISA

The Binding Activity of Human IL2RA with Anti-IL2RA Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA (CSB-MP011649HU3) at 2 μg/mL can bind Anti-IL2RA recombinant antibody , the EC50 is 2.463-3.353 ng/mL.

Recombinant Human Interleukin-2 receptor subunit alpha(IL2RA),partial (Active) CSB-MP011649HU3

验证数据

SDS
CSB-MP011649HU3 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
CSB-MP011649HU3 ELISA1

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bind Anti-IL2RA recombinant antibody (CSB-RA011649MA1HU),the EC50 is 2.463-3.353 ng/mL.

ELISA
CSB-MP011649HU3 ELISA2

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bindHuman IL2 (CSB-MP011629HU),the EC50 is 1.693-2.039 ng/mL.

IL2RA Antibodies

IL2RA for H

IL2RA for Homo sapiens (Human)

IL2RA Proteins

IL2RA Proteins for Bos taurus (Bovine)

IL2RA Proteins for Ovis aries (Sheep)

IL2RA Proteins for Felis catus (Cat) (Felis silvestris catus)

IL2RA Proteins for Rattus norvegicus (Rat)

IL2RA Proteins for Homo sapiens (Human)

IL2RA Proteins for Mus musculus (Mouse)

IL2RA Proteins for Sus scrofa (Pig)

IL2RA Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

IL2RA Proteins for Pan troglodytes (Chimpanzee)

IL2RA Proteins for Macaca mulatta (Rhesus macaque)

IL2RA ELISA Kit

IL2RA ELISA Kit for Homo sapiens (Human)

IL2RA ELISA Kit for Mus musculus (Mouse)