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中文名称:大鼠Tau蛋白酶联免疫试剂盒
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货号:CSB-E13729r
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规格:96T/48T
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价格:¥3900/¥2500
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其他:
产品详情
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产品描述:
This Rat MAPT ELISA Kit was designed for the quantitative measurement of Rat MAPT protein in serum, plasma, cerebrospinal fluid (CSF). It is a Sandwich ELISA kit, its detection range is 62.5 pg/mL-4000 pg/mL and the sensitivity is 15.6 pg/mL.
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别名:Mapt ELISA Kit; Mtapt ELISA Kit; Tau ELISA Kit; Microtubule-associated protein tau ELISA Kit; Neurofibrillary tangle protein ELISA Kit; Paired helical filament-tau ELISA Kit; PHF-tau ELISA Kit
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缩写:
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Uniprot No.:
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种属:Rattus norvegicus (Rat)
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样本类型:serum, plasma, cerebrospinal fluid (CSF)
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检测范围:62.5 pg/mL-4000 pg/mL
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灵敏度:15.6 pg/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Signal Transduction
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测定原理:quantitative
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测定方法:Sandwich
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精密度:
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
线性度:
To assess the linearity of the assay, samples were spiked with high concentrations of rat tau proteins in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:5 Average % 98 Range % 95-101 1:10 Average % 90 Range % 88-92 1:20 Average % 85 Range % 81-89 1:40 Average % 98 Range % 95-101 -
回收率:
The recovery of rat tau proteins spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 101 99-105 EDTA plasma (n=4) 87 84-90 -
标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. pg/ml OD1 OD2 Average Corrected 4000 2.694 2.678 2.686 2.523 2000 2.104 2.156 2.130 1.967 1000 1.330 1.356 1.343 1.180 500 0.825 0.836 0.831 0.668 250 0.552 0.568 0.560 0.397 125 0.359 0.368 0.364 0.201 62.5 0.276 0.298 0.287 0.124 0 0.167 0.159 0.163 -
数据处理:
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货期:3-5 working days
引用文献
- Natural inhibitors for acetylcholinesterase and autophagy modulators as effective antagonists for tau and β-amyloid in Alzheimer's rat model M Hassan,Biomarkers,2023
- Anti-aging trait of whey protein against brain damage of senile rats ME El-Beeh,Anti-aging trait of whey protein against brain damage of senile rats,2022
- Neuroprotective effect of peanut against oxidative stress in streptozotocin-induced diabetic rats NH Mohamed,Egyptian Journal of Basic and Applied Sciences,2022
- Electroacupuncture improves cognitive deficits and insulin resistance in an OLETF rat model of Al/D-gal induced aging model via the PI3K/Akt signaling pathway X Huang,Brain Res,2020
- The potential value of capsaicin in modulating cognitive functions in a rat model of streptozotocin-induced Alzheimer’s disease Manal A. Shalaby, et al,Febs Journal,2019
相关产品
问答及客户评论
靶点详情
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功能:Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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亚细胞定位:Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted.
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组织特异性:Expressed in neurons. The larger forms (isoform tau-A and isoform tau-B) are preferentially expressed in the peripheral nervous system while the other are expressed in the central nervous system. Low amounts of the larger forms are also found in limited a
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数据库链接:
STRING: 10116.ENSRNOP00000006856
UniGene: Rn.2455
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